Pfizer's UK Viagra patent set to expire this month
- 11 years ago
Pfizer, maker of blockbuster erectile dysfunction drug Viagra, is expected to face new competitors in the UK when its patent on the drug's process expires later this month. This animation explains the malfunctioning chemical process which Viagra's active ingredient treats.
During sexual arousal, the brain signals nerves fibers in arteries. These fibers release nitric oxide which triggers a chemical reaction. Cyclic guanosine monophosphate (cGMP) is then released causing the arteries' walls to relax, increasing blood flow and producing an erection." Meanwhile, the enzyme phosphodiesterase-5, (PDE5) is counteracting the cGMP. As long arousal continues, the heightened blood flow and erection is maintained. In cases of erectile disfunction, insufficient cGMP is produced and is overwhelmed by PDE5. Viagra contains a PDE inhibitor which bonds with the enzyme and stops it from counteracting the cGMP. This allows enough of the chemical to accumulate and relax the artery walls, producing an erection.
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During sexual arousal, the brain signals nerves fibers in arteries. These fibers release nitric oxide which triggers a chemical reaction. Cyclic guanosine monophosphate (cGMP) is then released causing the arteries' walls to relax, increasing blood flow and producing an erection." Meanwhile, the enzyme phosphodiesterase-5, (PDE5) is counteracting the cGMP. As long arousal continues, the heightened blood flow and erection is maintained. In cases of erectile disfunction, insufficient cGMP is produced and is overwhelmed by PDE5. Viagra contains a PDE inhibitor which bonds with the enzyme and stops it from counteracting the cGMP. This allows enough of the chemical to accumulate and relax the artery walls, producing an erection.
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TomoNews is your daily source for top animated news. We've combined animation and video footage with a snarky personality to bring you the biggest and best stories from around the world.
For news that's fun and never boring, visit our channel:
https://www.youtube.com/user/TomoNewsUS
Subscribe to stay updated on all the top stories:
http://www.youtube.com/subscription_center?add_user=TomoNewsUS
Stay connected with us here:
Facebook http://www.facebook.com/TomoNewsUS
Twitter @tomonewsus http://www.twitter.com/TomoNewsUS
Google+ http://gplus.to/TomoNewsUS